Mortal Kombat 1's Narrative Director, Dominic Ciancolo, har udtalt, at det kommende spils narrativ vil fungere som et "springbræt" for fremtidige spil i serien.
I et interview med ComicBook.com udtaler han følgende: "I think there's an expectation that was established because of MK9. That was obviously a speed run through the first three games. So we saw characters fully develop to what people knew them to be over the course of that one game. Mortal Kombat 1 as a narrative is a springboard. It's the first step on this road. And so we're going to obviously see the characters develop, they're going to change, things are going to happen, but this is not the end. This is just the beginning. And so that's going to be something we hopefully will evolve as we go forward."
Mortal Kombat 1 nulstiller tidslinjen og foregår i en version, hvor Liu Kang har smedet sin egen historie, men endnu ikke er fri for trusler. Spillet vil byde på både velkendte og nye ansigter, men det lader til, at selvom tidslinjen også blev nulstillet i det foregående spil, så er det historien i Mortal Kombat 1, der bliver seriens fundament fremvoer.