På trods af at han allerede har lagt navn til over 24 hæsblæsende sæsoner af Family Guy, viser Seth MacFarlane absolut ingen tegn på at trække stikket på den elskede, animerede komedieserie. Faktisk betragter MacFarlane fortsat serien som sit ultimative, kreative sikkerhedstæppe; seriens skaber og hovedstemme afslører nemlig, at han vil fortsætte med at spytte nye sæsoner ud i den nærmeste fremtid og holde franchisen langt væk fra det store lærred, indtil det en dag bliver absolut bydende nødvendigt at bringe Peter Griffin og resten af Quahog-banden i biografer verden over.
I et dybdegående interview med The Hollywood Reporter blev MacFarlane spurgt direkte, om vi nogensinde får en rigtig Family Guy-spillefilm at se. Hertil forklarede han ærligt, at det kort kun bliver spillet, hvis alt andet ramler:
"The Family Guy feature film is something that's still always in the back of my head. I've always had a pretty clear idea of what it's going to be. It's that arrow in the quiver that I keep for when everything else goes to shit. [Could that ever happen while the show is still on TV?] Oh, yeah. I always kind of assume that if I have a really dismal professional failure, like I produce a movie or a show that just fails so badly, the only thing that can cleanse the palette of the audience is the Family Guy movie. That's when I'll do it."
MacFarlane udtrykte samtidig sin dybe forundring over seriens ekstreme levedygtighed og popularitet:
"I think it can go as long as there's an appetite for it. I'm consistently shocked at the numbers for the show, that they continue to be very, very high. I don't know why that is. It's been so long. It's been a quarter of a century that this thing has been on the air!"