Under Microsoft's Build 2016-pressekonference gik Xbox-chefen Phil Spencer på scenen for at tale om PC-versionerne af Quantum Break og Forza Motorsports 6, og herigennem adresserede han ønsket om at få Halo 5: Guardians på PC. Han svarede følgende (opsamlet af PCGamer)
"In terms of Halo as a FPS on PC, I think there's a ton of opportunity for us right now, but I don't want to get into a world where we're looking back, like at Halo 5, That doesn't mean there's nothing there that could ever end up on PC, but I'd much rather look forward with what our plans are."